Section Contents:- There are millions of women who suffer from premenstrual dysphoric disorder (PMDD).(More...)
- In 1992, when Paxil hit the market, it faced a seemingly uphill battle to wrest customers from older SSRIs such as Prozac and Zoloft.(More...)
- PAXIL (paroxetine hydrochloride) is an orally administered psychotropic drug.(More...)
There are millions of women who suffer from premenstrual dysphoric disorder (PMDD). Too many of them are still waiting to feel relief. What do they have in common? Paxil CR may be right for them.
[4] The lawsuit alleged that GlaxoSmithKline promoted Paxil or Paxil CR for prescription to children and adolescents while withholding and concealing material information about the medication's safety and effectiveness for minors.
[3] According to the prescribing information provided by the manufacturer of Paxil brand of paroxetine GlaxoSmithKline and approved by the FDA, the effectiveness of paroxetine in major depressive disorder has been proven by six placebo-controlled clinical trials.
[3] Nearly a year ago, the U.S. Food and Drug Administration (FDA) and GlaxoSmithKline -- which makes Paxil -- changed the warnings on the drug to include the results of the studies. The FDA then advised pregnant women to merely switch from Paxil to another SSRI drug, such as Prozac or Zoloft.
[3] Paroxetine ( Seroxat, Paxil, Aropax, Xetanor, ParoMerck, Rexetin ) is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It was released in 1992 by the pharmaceutical company GlaxoSmithKline.
[3] The FDA's enhanced warning on Paxil followed the results of a review of Sweden's birth registry that found pregnant women who took Paxil were 1.5 to 2 times more likely to give birth to a baby with heart defects than women who took other SSRIs or who did not take antidepressants at all.
[3] The obstetric practice committee of the American College of Obstetricians and Gynecologists said pregnant women should not take Paxil because two previous studies found that the drug posed up to double the risk of heart defects in fetuses.
[3] Pregnant women and those who might become pregnant should avoid taking the antidepressant Paxil because of a high risk of birth defects, according to a committee of obstetricians who published their opinion in the December 2006 issue of the journal Obstetrics & Gynecology.
[3] In May 2007 a U.S. court approved a settlement in a class action lawsuit brought on behalf of everyone in the United States who purchased Paxil or Paxil CR prescribed for a minor.
[3] The settlement terms entitled everyone, who previously purchased Paxil or Paxil CR for the child or ward, to recover up to 100% of the documented out-of-pocket expenses or $100, if the documentation was not available.
[3] Neonatal withdrawal symptoms from Paxil have also been documented from mothers taking Paxil during pregnancy.
[3] 
In 1992, when Paxil hit the market, it faced a seemingly uphill battle to wrest customers from older SSRIs such as Prozac and Zoloft. The U.S. Food and Drug Administration had approved Paxil for the treatment of depression, like those drugs. Its manufacturer, SmithKline Beecham (because of a 2001 merger, now GlaxoSmithKline), was more interested in positioning Paxil as a remedy for anxiety disorders.
[2] When the drug was introduced in 1992, the market seemed so saturated with antidepressants that it was hard to imagine Paxil would ever catch up. A decade later, it's poised to become the world's best-selling SSRI. GlaxoSmithKline has steadily and energetically added to the list of disorders Paxil can be used to treat, and spent billions of dollars to make sure the buying public knows where to turn in case anxiety or melancholy sets in.
[2] Last year, GlaxoSmithKline won FDA approval to sell Paxil for generalized anxiety disorder, a diagnosis that was created by psychiatrists as something of a catchall entry in the Diagnostic and Statistical Manual of Mental Disorders.
[2] The company quickly secured permission to market Paxil for the treatment of panic disorder and obsessive-compulsive disorder.
[2] In 1996, sales of the drug had climbed 54 percent to $291 million. Impressive though those numbers may be, SmithKline was on the verge of a much bigger marketing coup: The company had been working to win approval from the U.S. Food and Drug Administration to market Paxil as a treatment for the first of a series of little-known mental health ills.
[2] Paxil was the first central-nervous-system drug to be advertised by name on television, according to Advertising Age. With such tag lines as "Your life is waiting" and "What if you were allergic to people?", the spots targeted 18-to-34-year-old professionals.
[2] For years Eli Lilly's Prozac was the most widely prescribed SSRI. Pfizer's Zoloft has likewise taken a turn as the top seller. It's Paxil that has shone as a marketer's dream.
[2] "Paxil belongs to a class of medications called SSRIs, which have not been shown to be associated with addiction."
[2] By mid-1995, Paxil had become the fastest-growing SSRI in the United States.
[2] For tens of millions of Americans, Paxil and its pharmaceutical cousins--Prozac, Zoloft, Celexa, and Luvox--have proven a godsend. They boast far fewer side effects than their predecessors and it's virtually impossible to take a lethal quantity of the new pills.
[2] Unfortunately GlaxoSmithKline leaves out one little detail: For thousands of people, it seems that Paxil could well be addictive.
[2] In the weeks following the attack on the World Trade Center, Glaxo positioned Paxil as the perfect antidote to post-9/11 anxiety.
[2] In 1999, the FDA agreed to allow Paxil's prescription for the previously rare "social anxiety disorder."
[2] "Paxil's reintroduction secured nearly 1.1 billion media impressions in 1999, with 400 million generated in the month that the drug was granted FDA approval," raved PR News.
[2] PAXIL (paroxetine hydrochloride) is an orally administered psychotropic drug. It is the hydrochloride salt of a phenylpiperidine compound identified chemically as (-)- trans -4 R -(4'-fluorophenyl)-3 S - piperidine hydrochloride hemihydrate and has the empirical formula of C 19 H 20 FNO 3 •HCl•½H 2 O. The molecular weight is 374.8 (329.4 as free base).
[5] Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of PAXIL or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need.
[5] Paxil is sometimes used to treat OCD. Find additional health information on obsessive compulsive disorder
obsessive compulsive disorder including other treatment options at WebMD.com.
[5] SSRIs/SNRI/Triptan and Serotonin Syndrome (7/2006) A life-threatening condition called serotonin syndrome (serious changes in how your brain, muscles and digestive system work due to high levels of serotonin in the body) can happen when medicines called selective serotonin reuptake inhibitors (SSRIs), such as Paxil, and medicines used to treat migraine headaches known as 5-hydroxytryptamine receptor agonists (triptans), are used together.
[6] Before you take Paxil and a triptan together, talk to your healthcare professional. If you must take these medicines together, be aware of the possibility of serotonin syndrome, and get medical care right away if you think serotonin syndrome is happening to you.
[6] Paxil helps a lot of people like me who suffer from depression and social anxiety. I hope your article doesn't steer them away from getting the help they need.
[7] You don't sound like you had social anxiety or depression, the two illnesses for which the FDA has approved Paxil.
[7] As best I can tell, Paxil works by creating massive detachment from your own emotions. If your social anxiety verges on looniness, detachment from those emotions is a good thing.
[7] When I get teary-eyed watching a horrid chick-flick on a cross-country flight, I recognize it: feelings. On Paxil, I barely noticed they were gone. Now that they're back, even overcompensating, I never want to lose them again. Bitterness, anger, jealousy, sadness: They all make me happy.
[7] As a sort of New Year resolution, I have been examining the Paxil sites on the Internet and came very close to ordering directly online and shelling out $200.00 for my new outlook for the new millenium.
[7] I'm guessing many of you are no different. I've often wondered what it's like to be outgoing"a social butterfly, an extrovert. That's why TV ads for Paxil caught my eye. You've seen them: They promise ease in a pill.
[7] Could it be Paxil's antidepressant effects? Perhaps I'm too content to be motivated. Do I require bile and unhappiness to write? I could clearly go the rest of my life on this stuff and never feel down again. Another scary part: Before Paxil, while working on stories, turns of phrase would pop into my head, fully formed.
[7] After deciding Paxil is worthless and downing three glasses of wine, I find I want to talk to people.
[7] 
